Myeloma and the immune system:a new era

Fotis Asimakopoulos

Associate Professor, Medicine

Scientific Director,

UW Myeloma Program

Asimakopoulos et al., J Leuk Biol, 2017

How the immune system recognizes cancer

At the Sistine Chapel….

Dendritic cell vaccines

Checkpoint inhibitors

Daratumumab (darzalex)

CAR-T cells

•UW Myeloma Study Group & Collaborators

•Paul Sondel•Sasha Rakhmilevich•Dusty Deming, •Phil Emmerich•Peiman Hematti•Dave Schwartz•Natalie Callander•Shigeki Miyamoto•Jing Zhang•Shannon Kenney•Catherine Leith•Emery Bresnick•Alan Rapraeger

•External Collaborators•Marta Chesi•Leif Bergsagel•Ioanna Maroulakou•Constantine Mitsiades•Scott Abrams•Parameswaran Hari,

Binod Dhakal•Sundar Jagannath•Suneel Apte

Asimakopoulos lab

➢Chelsea Hope

➢Michael Johnson

➢Adam Pagenkopf

➢Thanos Papadas

➢Kim Gromek

➢Bradley Nagel

➢Elena Kurudza

➢Samik Partha

Funding:

American Cancer SocietyResearch Scholar Grant

Leukemia and Lymphoma Society Translational Program Grant

UWCCC Trillium Myeloma Fund